We are a late-stage biotech company focused on addressing diseases of the central nervous system (CNS).

Our most advanced program is REL-1017, a novel NMDA receptor (NMDAR) channel blocker that preferentially targets hyperactive channels associated with major depressive disorder (MDD), while maintaining physiological glutamatergic neurotransmission. We believe that REL-1017 has the potential to transform the current neuropharmacological approach to MDD, and we are rapidly advancing toward our initial target indication, which is adjunctive treatment for MDD in adults.

Depression represents the largest cause of disability around the world¹. Our dedicated team is focused on moving REL-1017 forward as a potentially transformational option for people living with MDD.

Based on our Phase 1 and Phase 2 studies, we believe there is a real potential for REL-1017 to treat MDD safely, effectively, and more quickly than is currently possible with a well-tolerated, oral, once-daily tablet. REL-1017 received Fast Track Designation and has entered the pivotal Phase 3 program as an adjunctive treatment for MDD in adults.

We are growing our company accordingly as we execute our Phase 3 program: RELIANCE I, RELIANCE II and RELIANCE-OLS for REL-1017. We have assembled an experienced development team to advance this promising program.